B-BIC: Translating Discoveries Into Products

connecting

Connecting the academic and commercial sectors

funding

Providing non-dilutive funding and more

built

Built with 13 institutions and the NIH

weare

Boston Biomedical Innovation Center (B-BIC) is a life sciences accelerator funded by the National Institutes of Health and our member institutions to increase the return on investment in research. We speed the translation of research technologies into products for doctors and their patients, for the good of society.

Our members are a consortium of academic medical centers in Boston including Brigham and Women’s Hospital, Harvard Medical School, Massachusetts General Hospital, and the Massachusetts Institute of Technology.

grant-funding
coaching
project-mgmt
skills-dev
ext-partners
Grant Funding
Coaching
Project Management
Skills Development
External Partnerships
Grant Funding

B-BIC provides funding for technology development and translational research, including regulatory, reimbursement, and business development aspects that are part of an overall commercialization strategy

Coaching

B-BIC provides coaching  for investigators  to help them develop commercialization strategies for their technologies.

Coaches help PIs  with market assessment, competitive analysis, business models, regulatory and reimbursement paths, and overall risks that may be associated with their project plans. B-BIC coaches all have extensive experience successfully commercializing technologies.

Project Management

B-BIC project managers bring decades of industry experience and actively engage with investigators to identify, prioritize, and refine objectives, develop critical path-driven project plans, and manage projects to successful exit from the Center. Project Managers work with investigators as part of the team to:

  • Manage development and implementation of the project plan from inception to exit from B-BIC
  • Identify linkages and dependencies between research, development and commercialization activities
  • Identify and assist in the selection of vendors and critical external resources needed to support completion of project milestones
  • Facilitate interactions between investigators and relevant external partners (FDA, CMS, industry)
Skills Development

B-BIC offers courses, workshops, expert advisors and community events focused on technology commercialization.  DRIVE awards also include custom skills development consultations to integrate both PI experience and the needs of the project with the project milestones.

External Partnerships

B-BIC provides access to key Federal partners including the Food and Drug Administration (FDA), the Center for Medicare and Medicaid Services (CMS), the U.S. Patent and Trade Office (USPTO), relevant companies and organizations within  industry, and the angel and venture capital investment communities.

Members of the Boston venture capital community review and engage with our funded projects as part of our Technology Assessment and Development Group.  Investigators also have the opportunity to present to the group as a whole when their projects could benefit from TADG members’ perspectives and input.

Representatives from our Federal partners, the FDA, CMS, and the USPTO also provide input into each of our funded projects and are available for consultation via our Project Managers.

Clinical Domains

Heart
Lung
Blood
Sleep

Technical Domains

Device
Diagnostic
Therapeutic

Success Story: Jonathan Thon and Platelet Biogenesis, Inc

October 25, 2016

Platelets are the ‘bandaids’ of the bloodstream. They are the cells in your blood that stop you from bleeding and transfusions save the lives of millions every year. However, platelets can only be stored for 5-7.5 days because of bacterial contamination issues. To manage this, blood centers typically don’t keep more than a 1.5 days…

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Success Story: Warren Zapol, David Zapol and Third Pole, Inc.

October 25, 2016

Approximately 10,000 “blue babies” are given inhaled nitric oxide (NO) to treat Hypoxic Respiratory Failure each year. Other potential uses for inhaled NO include heart attacks, strokes, and malaria. But the technology necessary to deliver inhaled NO is available only in a limited number of countries, for those who can afford it, with physicians who…

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Testimonial: Program Invaluable

October 27, 2016

The B-BIC program has been invaluable in two ways. First, the grant support has allowed us to bring our device from early prototyping stage to full preclinical testing and now at a point where we can focus on achieving FDA clearance for clinical use. Second, the support of advisors have taught me to navigate the…

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Testimonial: Increased Visibility

October 27, 2016

Progress made under this award has increased my visibility to pharmaceutical companies so that I have been sought as an investigator for several companies.

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Testimonial: Broadened Horizons

October 27, 2016

This project has advanced my professional development objectives by allowing me to learn much about the technology development and commercialization process. Beyond my conventional academic pursuits, involvement with the B-BIC program has broadened my horizons and underlined the importance of translating promising science from our laboratories towards practical/commercial applications. This work has enhanced my interest…

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Testimonial: Business Principles Advanced

October 27, 2016

This grant has enabled me to advance the development of a medical device with a high potential clinical impact. This is consistent with my academic career, which centers on translational imaging research. The B-BIC grant has allowed me to engage with marketing and business advisors to learn more deeply about practical business principles necessary to…

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Testimonial: Clear Objectives

October 27, 2016

B-BIC has been a communicative and supportive organization to work with and the program is well designed. B-BIC has chosen targeted topics and emphasized commercial translation, making the program objectives clear. This aids the proposer in assessing likelihood of winning an award. The involvement of the program managers has been helpful and informative. The proposal…

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Testimonial: Challenging Interaction a Huge Plus

October 27, 2016

Here is how B-BIC has helped this project. The money itself. It would be very difficult to raise money for this project from standard sources. Challenging questions from the reviewers. During the review of our preproposal, one challenge from the B-BIC point of contact was that we should design a Phase 3 trial for our…

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Testimonial: Resolving Hurdles

October 27, 2016

The B-BIC program has been instrumental in helping us accelerate development of our bioreactor and achieve commercial proof of feasibility that would not have been possible within the same time frame by traditional non-dilutive funding mechanisms available at the time. B-BIC also allowed us to bridge academic and commercial requirements and resolve many practical hurdles…

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