RECIPIENT:  Dr. Michael Sweeney TITLE: SQPAN TYPE OF AWARD:  PILOT INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Cardiac resynchronization therapy (CRT) is an electrical therapy using multi-site cardiac pacing to re-time the asynchronous contraction sequence of the failing heart on a beat-to-beat basis. Worldwide randomized clinical trials have consistently demonstrated that effective CRT induces reverse ventricular remodeling, which is followed…

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RECIPIENT:  Dr. Paul Yu TITLE: Molecular Imaging of Dysregulated Angiogenesis in Pulmonary Arterial Hypertension TYPE OF AWARD:  DRIVE INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:   Pulmonary arterial hypertension (PAH) is a disorder of elevated pulmonary vascular resistance characterized by progressive remodeling and obliteration of resistance-determining vessels of the pulmonary circulation. Despite current therapies, transplant-free survival…

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RECIPIENT:  Dr. Jill Goldstein TITLE: Development of an electroceutical for treatment of comorbidity between hypertension and major depression. TYPE OF AWARD:  DRIVE INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Hypertension is a leading cause of morbidity and mortality in the United States with an overall prevalence of approximately 29%, corresponding to 70 million of Americans. Despite the benefits…

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  Who can apply for B-BIC grants? Anyone holding a faculty appointment at a B-BIC member institution may apply for a B-BIC grant. May I submit more than one application? Applicants may submit more than one proposal to both the Pilot and DRIVE programs.  However, each application must have a distinct set of aims and…

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