TITLE: Humanized anti-DEspR antibody therapy for acute respiratory distress syndrome TYPE OF AWARD: Drive CLINICAL AREA:  Lung INSTITUTION: Boston University DESCRIPTION: Acute respiratory distress syndrome (ARDS) and its progression to multi-organ failure (MOF) affects ~200,000 ICU patients each year in the US, with high mortality and healthcare costs. ARDS is driven by hyperinflammation-injury cycles that begin as a normal injury…

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TITLE: Generation of a Novel Therapeutic Antibody for Treatment of Allergic Asthma TYPE OF AWARD: Pilot CLINICAL AREA:  Lung INSTITUTION: Brigham and Women’s Hospital   DESCRIPTION: Asthma affects 8% of the US population, approximately 25 million people. About 10% of patients have severe asthma, accounting for an estimated 1.8 million emergency department visits, 439,000 hospitalizations, and 3,630 deaths annually…

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Written by Erin McKenna, B-BIC Deputy Director There are multiple frameworks out there that outline the process for developing promising biomedical research into a range of innovative solutions – pharmaceuticals, biologics, medical devices, and diagnostics.  Many of these processes leverage concepts that come from regulations developed by the FDA, the European Commission and others to…

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Over the course of 2019, our coaches and staff broke down the B-BIC application process to provide you with expert advice on all the of the questions we ask you to answer when applying for our program. For those who are not applying yet, the B-BIC proposal has many similarities to a business plan, which…

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