New Award

New Award: Congratulations Dr. Darren Roblyer

TITLE: CardioptOx: A new real-time quantitative cardio-pulmonary monitoring technique for improved patient care. TYPE OF AWARD: Pilot TECHNOLOGY TYPE: Diagnostic Device CLINICAL AREA:  Heart INSTITUTION: Boston University DESCRIPTION: Approximately 600,000 deaths per year are attributed to cardiopulmonary disease in the US. Many patients suffering from cardiopulmonary disease experience complications that require hospital and intensive care unit (ICU) stays.…

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New Award: Congratulations, Dr. Jonghan Kim!

RECIPIENT:  Dr. Jonghan Kim TITLE: Hydrogel-based nanochelator therapy for iron overload disorders TYPE OF AWARD: Drive TECHNOLOGY TYPE: Small Molecule CLINICAL AREA: Blood INSTITUTION: Northeastern & MGH DESCRIPTION: Iron overload, best represented by hereditary hemochromatosis (primary/genetic iron overload) and transfusional hemoglobinopathy (secondary/acquired iron overload), is a well-defined risk factor for several critical diseases, including heart failure, liver cirrhosis, arthritis,…

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NEW AWARD: CONGRATULATIONS DR J. BRIAN MCALVIN

RECIPIENT:  Dr. J. Brian McAlvin TITLE: A Novel Method To Treat The Systemic Inflammatory Response Syndrome (SIRS) TYPE OF AWARD: Pilot TECHNOLOGY TYPE: Therapeutic Device CLINICAL AREA: Blood INSTITUTION: Boston Children’s Hospital DESCRIPTION: We have developed highly-selective blood-filtering devices that are capable of filtering of individual, harmful molecules from the blood of patients rendered critically ill by the…

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NEW AWARD: CONGRATULATIONS, DR. SYLVIE BRETON!

RECIPIENT:  Dr. Sylvie Breton TITLE: Predicting and Preventing Acute Kidney Injury Associated with Cardiovascular Diseases TYPE OF AWARD:  PILOT TECHNOLOGY TYPE: Small Molecule Drug CLINICAL AREA: Heart INDICATION: Acute Kidney Injury INSTITUTION: MGH DESCRIPTION:  Acute kidney injury (AKI) is a frequent complication of hospitalized patients. Unfortunately, there is no cure for this potentially deadly condition. Thus, a critical…

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NEW AWARD: CONGRATULATIONS DR. NELSON RUIZ – OPAZO

RECIPIENT:  Dr. Nelson Ruiz – Opazo TITLE: Fully humanized anti-DEpR antibody therapy for acute lung injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) TYPE OF AWARD:  PILOT TECHNOLOGY TYPE: Biologic Drug CLINICAL AREA: Lung INDICATION: Acute Lung Injury / Acute Respiratory Distress Syndrome INSTITUTION: Boston University DESCRIPTION:The feed-forward progression of acute lung injury (ALI) towards acute respiratory distress syndrome (ARDS)…

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NEW AWARD: CONGRATULATIONS DR. LEO TSAI!

RECIPIENT: Dr. Leo Tsai TITLE: A Novel Coaxial Deflectable Microcatheter for Rapid Navigation of Tortuous Vessels TYPE OF AWARD: DRIVE INSTITUTION: Beth Israel Deaconess Medical Center TECHNOLOGY TYPE: Therapeutic Device DESCRIPTION: Microcatheters are used to access small vessels throughout the body to treat a wide variety of pathology, from traumatic hemorrhage to tumors. Selection of…

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NEW AWARD: CONGRATULATIONS DR. BEN MATTHEWS

RECIPIENT:  Dr. Ben Matthews TITLE: PR1P, an inhaled novel short peptide for emphysema TYPE OF AWARD:  PILOT INSTITUTION: Boston Children’s Hospital DESCRIPTION:  Emphysema is a chronic progressive pulmonary disease characterized by destruction of alveoli leading to impaired lung function that threatens human health worldwide. Disease progression is due in part to dysregulation of the survival factor Vascular Endothelial Growth Factor (VEGF). …

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NEW AWARD: CONGRATULATIONS DR. MICHAEL SWEENEY!

RECIPIENT:  Dr. Michael Sweeney TITLE: SQPAN TYPE OF AWARD:  PILOT INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Cardiac resynchronization therapy (CRT) is an electrical therapy using multi-site cardiac pacing to re-time the asynchronous contraction sequence of the failing heart on a beat-to-beat basis. Worldwide randomized clinical trials have consistently demonstrated that effective CRT induces reverse ventricular remodeling, which is followed…

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NEW AWARD: CONGRATULATIONS DR. PAUL YU!

RECIPIENT:  Dr. Paul Yu TITLE: Molecular Imaging of Dysregulated Angiogenesis in Pulmonary Arterial Hypertension TYPE OF AWARD:  DRIVE INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:   Pulmonary arterial hypertension (PAH) is a disorder of elevated pulmonary vascular resistance characterized by progressive remodeling and obliteration of resistance-determining vessels of the pulmonary circulation. Despite current therapies, transplant-free survival…

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NEW AWARD: CONGRATULATIONS DR. JILL GOLDSTEIN!

RECIPIENT:  Dr. Jill Goldstein TITLE: Development of an electroceutical for treatment of comorbidity between hypertension and major depression. TYPE OF AWARD:  DRIVE INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Hypertension is a leading cause of morbidity and mortality in the United States with an overall prevalence of approximately 29%, corresponding to 70 million of Americans. Despite the benefits…

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