B-BIC: Translating Discoveries Into Products

connecting

A road map to commercialization

funding

Grant funding up to $350,000 per project

built

Built with 13 institutions and the NIH

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Boston Biomedical Innovation Center (B-BIC) is a life sciences accelerator funded by the National Institutes of Health and our member institutions to increase the return on investment in research. We speed the translation of research technologies into products for doctors and their patients, for the good of society.

Our members are a consortium of academic medical centers in Boston including Brigham and Women’s Hospital, Harvard Medical School, Massachusetts General Hospital, and the Massachusetts Institute of Technology.

grant-funding
coaching
project-mgmt
skills-dev
ext-partners
Grant Funding

B-BIC provides funding for technology development and translational research, including regulatory, reimbursement, and business development aspects that are part of an overall commercialization strategy.

Coaching
Project Management
Skills Development
External Partnerships

Clinical Domains

Heart
Lung
Blood
Sleep

Technical Domains

Device
Diagnostic
Therapeutic

NEW AWARD: CONGRATULATIONS, DR. SYLVIE BRETON!

November 10, 2017

RECIPIENT:  Dr. Sylvie Breton TITLE: Predicting and Preventing Acute Kidney Injury Associated with Cardiovascular Diseases TYPE OF AWARD:  PILOT TECHNOLOGY TYPE: Small Molecule Drug CLINICAL AREA: Heart INDICATION: Acute Kidney Injury INSTITUTION: MGH DESCRIPTION: One third of cardiac surgery patients and 22% of patients with acute myocardial infarction will develop AKI. AKI diagnosis leads to longer hospital…

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NEW AWARD: CONGRATULATIONS DR. NELSON RUIZ – OPAZO

October 30, 2017

RECIPIENT:  Dr. Nelson Ruiz – Opazo TITLE: Fully humanized anti-DEpR antibody therapy for acute lung injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) TYPE OF AWARD:  PILOT TECHNOLOGY TYPE: Biologic Drug CLINICAL AREA: Lung INDICATION: Acute Lung Injury / Acute Respiratory Distress Syndrome INSTITUTION: Boston University DESCRIPTION:The feed-forward progression of acute lung injury (ALI) towards acute respiratory distress syndrome (ARDS)…

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FAST PITCH FOR FUNDING: FAQ

September 12, 2017

Q:  Do I need to have slides?  A:  Pitches only need to address the suggested elements.  Use of reference materials or other visual elements is welcome if they help convey the product concept and can be shared using your laptop screen.  AV equipment will not be available. Q:  How formal will the pitches be? A:…

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FAST PITCH FOR FUNDING: Quick Tips for a successful pitch

September 12, 2017

Keep pitch short and focused on the technology and its commercial application. Limit the discussion of preliminary results, and focus on the most relevant results with conclusions – not data. Present the science within the context of the business strategy.   This FAST PITCH FOR FUNDING is November 3, 2017 at 10:00am at Harvard Medical School.  This event provides…

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NEW AWARD: CONGRATULATIONS DR. LEO TSAI!

September 5, 2017

RECIPIENT: Dr. Leo Tsai TITLE: A Novel Coaxial Deflectable Microcatheter for Rapid Navigation of Tortuous Vessels TYPE OF AWARD: DRIVE INSTITUTION: Beth Israel Deaconess Medical Center TECHNOLOGY TYPE: Therapeutic Device DESCRIPTION: Microcatheters are used to access small vessels throughout the body to treat a wide variety of pathology, from traumatic hemorrhage to tumors. Selection of…

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NEW AWARDS: B-BIC selects five new technologies to award support for commercial development

July 7, 2016

RECIPIENT:  Dr. Pamela Silver TITLE: A Targeted Erythropoietin-Based Therapeutic TYPE OF AWARD:  DRIVE INSTITUTION: Harvard Medical School DESCRIPTION:  Pamela Silver, PhD., Elliot T and Onie H Adams Professor of Biochemistry and Systems Biology, Harvard Medical School, and a founding member of the Wyss Institute was awarded a DRIVE grant for continued development of a targeted erythropoietin-based therapeutic.  EPO plays…

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NEW AWARDS: B-BIC selects three new technologies to award support for commercial development.

April 7, 2016

RECIPIENT:  Dr. Ehud Schmidt TITLE: An MRI-Compatible Voltage Device Tracking For Multimodality Electrophysiology TYPE OF AWARD:  PILOT INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Ehud Schmidt, PhD, Director of Engineering Physics in the Department of Radiology, Brigham and Women’s Hospital, and Associate Professor at Harvard Medical School receives a Pilot award to develop MRI-compatible voltage device tracking for multimodality…

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NEW AWARDS: B-BIC Supports New Technologies For Commercial Development

January 6, 2016

RECIPIENT: Dr. Warren Zapol TITLE: Portable and Affordable Lightweight NO Generator TYPE OF AWARD:  DRIVE INSTITUTION: MGH DESCRIPTION:  Warren Zapol, MD, Director of the MGH Anesthesia Center for Critical Care Research at Massachusetts General Hospital, receives a DRIVE award to develop electric nitric oxide generation for medical purposes.  Inhaled nitric oxide (NO) was approved by the FDA…

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NEW AWARD: CONGRATULATIONS DR. BEN MATTHEWS

June 9, 2017

RECIPIENT:  Dr. Ben Matthews TITLE: PR1P, an inhaled novel short peptide for emphysema TYPE OF AWARD:  PILOT INSTITUTION: Boston Children’s Hospital DESCRIPTION:  Emphysema is a chronic progressive pulmonary disease characterized by destruction of alveoli leading to impaired lung function that threatens human health worldwide. Disease progression is due in part to dysregulation of the survival factor Vascular Endothelial Growth Factor (VEGF). …

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NEW AWARD: CONGRATULATIONS DR. JILL GOLDSTEIN!

May 15, 2017

RECIPIENT:  Dr. Jill Goldstein TITLE: Development of an electroceutical for treatment of comorbidity between hypertension and major depression. TYPE OF AWARD:  DRIVE INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Hypertension is a leading cause of morbidity and mortality in the United States with an overall prevalence of approximately 29%, corresponding to 70 million of Americans. Despite the benefits…

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NEW AWARD: CONGRATULATIONS DR. PAUL YU!

May 15, 2017

RECIPIENT:  Dr. Paul Yu TITLE: Molecular Imaging of Dysregulated Angiogenesis in Pulmonary Arterial Hypertension TYPE OF AWARD:  DRIVE INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:   Pulmonary arterial hypertension (PAH) is a disorder of elevated pulmonary vascular resistance characterized by progressive remodeling and obliteration of resistance-determining vessels of the pulmonary circulation. Despite current therapies, transplant-free survival…

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NEW AWARD: CONGRATULATIONS DR. MICHAEL SWEENEY!

May 15, 2017

RECIPIENT:  Dr. Michael Sweeney TITLE: SQPAN TYPE OF AWARD:  PILOT INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Cardiac resynchronization therapy (CRT) is an electrical therapy using multi-site cardiac pacing to re-time the asynchronous contraction sequence of the failing heart on a beat-to-beat basis. Worldwide randomized clinical trials have consistently demonstrated that effective CRT induces reverse ventricular remodeling, which is followed…

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Success Story: Warren Zapol, David Zapol and Third Pole, Inc.

October 25, 2016

Approximately 10,000 “blue babies” are given inhaled nitric oxide (NO) to treat Hypoxic Respiratory Failure each year. Other potential uses for inhaled NO include heart attacks, strokes, and malaria. But the technology necessary to deliver inhaled NO is available only in a limited number of countries, for those who can afford it, with physicians who…

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Success Story: Jonathan Thon and Platelet Biogenesis, Inc

October 25, 2016

Platelets are the ‘bandaids’ of the bloodstream. They are the cells in your blood that stop you from bleeding and transfusions save the lives of millions every year. However, platelets can only be stored for 5-7.5 days because of bacterial contamination issues. To manage this, blood centers typically don’t keep more than a 1.5 days…

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