B-BIC: Translating Discoveries Into Products

connecting

A road map to commercialization

funding

Grant funding up to $350,000 per project

built

Built with 14 institutions and the NIH

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Boston Biomedical Innovation Center (B-BIC) is a life sciences accelerator funded by the National Institutes of Health and our member institutions to increase the return on investment in research. We speed the translation of research technologies into products for doctors and their patients, for the good of society.

Our members are a consortium of academic medical centers in Boston including Brigham and Women’s Hospital, Harvard Medical School, Massachusetts General Hospital, and the Massachusetts Institute of Technology.

grant-funding
coaching
project-mgmt
skills-dev
ext-partners
Grant Funding

B-BIC provides funding for technology development and translational research, including regulatory, reimbursement, and business development aspects that are part of an overall commercialization strategy.

Coaching
Project Management
Skills Development
External Partnerships

Clinical Domains

Heart
Lung
Blood
Sleep

Technical Domains

Device
Diagnostic
Therapeutic

Reimbursement Basics

October 19, 2018

Contributed by Ed Berger Principal Larchmont Strategic Advisors Reimbursement strategy counsel to companies across the life sciences spectrum   A basic understanding of the healthcare reimbursement system is an important success factor for any entrepreneur developing a new medical product. Reimbursement is critical to opportunity assessment, business plan development, investor due diligence, and commercial success.  The…

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FAST PITCH FOR FUNDING: Quick Tips for a successful pitch

August 14, 2018

Keep pitch short and focused on the technology and its commercial application. Limit the discussion of preliminary results, and focus on the most relevant results with conclusions – not data. Present the science within the context of the business strategy.   FAST PITCH FOR FUNDING is Friday, October 12, 2018  from 10am – 12pm at TUFTS UNIVERSITY, 145 Harrison Ave, Room…

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FAST PITCH FOR FUNDING: FAQ

February 5, 2018

Q:  Do I need to have slides?  A:  Pitches only need to address the suggested elements.  Use of reference materials or other visual elements is welcome if they help convey the product concept and can be shared using your laptop screen.  AV equipment will not be available. Q:  How formal will the pitches be? A:…

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Specialist Series: A Brief Introduction to Intellectual Property

September 11, 2018

Contributed by Lesley Watts, Director of B-BIC Operations & Finance Intellectual property is the product of a person’s creativity and it can take several forms including patents, copyright, trademarks, and trade secrets.  Patents play a key role in innovation and economic development, particularly in the life sciences, because they allow the patent holder to capture the…

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Success Stories: B-BIC’s Work With Platelet Biogenesis

September 11, 2018

WATCH:  B-BIC’s Work With Platelet Biogenesis One of B-BIC’s first grant recipients was Jonathan Thon, a researcher based at Brigham and Women’s Hospital. Jonathan and his team had been researching two technologies necessary for producing platelets outside of the body. They had achieved promising results that demonstrated a microfluidic platform could simulate bone marrow physiological…

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Specialist Series: The Regulatory Path

April 17, 2018

Contributed by John Randle, Phd B-BIC COACH PRINCIPAL, RANDOM WALK VENTURES, LLC COO, KANTUM BIO   Most new technologies and products will require regulatory scrutiny and approval prior to marketing.  These requirements vary widely depending on the nature of the technology/product and their intended medical use, as well as the regulatory precedent set by existing…

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New Awards: B-BIC selects three new technologies to award support for commercial development.

April 7, 2016

RECIPIENT:  Dr. Ehud Schmidt TITLE: An MRI-Compatible Voltage Device Tracking For Multimodality Electrophysiology TYPE OF AWARD:  PILOT INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Ehud Schmidt, PhD, Director of Engineering Physics in the Department of Radiology, Brigham and Women’s Hospital, and Associate Professor at Harvard Medical School receives a Pilot award to develop MRI-compatible voltage device tracking for multimodality…

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New Awards: B-BIC Supports New Technologies For Commercial Development

January 6, 2016

RECIPIENT: Dr. Warren Zapol TITLE: Portable and Affordable Lightweight NO Generator TYPE OF AWARD:  DRIVE INSTITUTION: MGH DESCRIPTION:  Warren Zapol, MD, Director of the MGH Anesthesia Center for Critical Care Research at Massachusetts General Hospital, receives a DRIVE award to develop electric nitric oxide generation for medical purposes.  Inhaled nitric oxide (NO) was approved by the FDA…

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Specialist Series: How to build an effective overview of your technology.

October 30, 2017

Contributed by Erin McKenna, B-BIC Deputy Director After the dip in investment in early-stage biotechnology in 2008, the number of funding opportunities for early-stage technologies has been increasing in recent years. Despite this promising trend, finding and securing the funding necessary to move your research out of the lab and towards commercialization is still a…

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Specialist Series: Finding and Defining Your Unmet Need

November 10, 2017

Contributed by Josh Tolkoff The most common reason for the commercial failure of a start-up entity is not having a compelling clinical need.  What exactly is an “unmet need”?  An unmet need is something more than an incremental improvement, and once it exists in the market it will make a substantial change for the better.…

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Specialist Series: Filling the Unmet Need – Your Proposed Solution

December 11, 2017

Contributed by Ron Blackman In our previous newsletter, we described how to identify the unmet need that will be served by your device or therapeutic, and here we will help you build the case that you have a solution to meet that need.  A number of points should be addressed and we will go through…

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Specialist Series: Defining Your Competitive Landscape

January 31, 2018

Contributed by John Randle, Phd B-BIC COACH PRINCIPAL, RANDOM WALK VENTURES, LLC COO, KANTUM BIO The first step in defining your competitive landscape is to identify and define the technology’s current competition and how they fit into or define current standard of care (SoC).  List the products or substitutes that you would aim to replace…

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Specialist Series: Defining Your Market 

March 1, 2018

Contributed by John Randle, Phd B-BIC COACH PRINCIPAL, RANDOM WALK VENTURES, LLC COO, KANTUM BIO As you prepare to move your technology or product out of the academic setting towards commercial development, a key step is to define the market potential for your technology/product.  Prospective investors will assess the opportunity in terms of the potential…

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New Award: Congratulations, Dr. Jonghan Kim!

February 26, 2018

RECIPIENT:  Dr. Jonghan Kim TITLE: Hydrogel-based nanochelator therapy for iron overload disorders TYPE OF AWARD: Drive TECHNOLOGY TYPE: Small Molecule CLINICAL AREA: Blood INSTITUTION: Northeastern & MGH DESCRIPTION: Iron overload, best represented by hereditary hemochromatosis (primary/genetic iron overload) and transfusional hemoglobinopathy (secondary/acquired iron overload), is a well-defined risk factor for several critical diseases, including heart failure, liver cirrhosis, arthritis,…

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NEW AWARD: CONGRATULATIONS DR J. BRIAN MCALVIN

January 31, 2018

RECIPIENT:  Dr. J. Brian McAlvin TITLE: A Novel Method To Treat The Systemic Inflammatory Response Syndrome (SIRS) TYPE OF AWARD: Pilot TECHNOLOGY TYPE: Therapeutic Device CLINICAL AREA: Blood INSTITUTION: Boston Children’s Hospital DESCRIPTION: We have developed highly-selective blood-filtering devices that are capable of filtering of individual, harmful molecules from the blood of patients rendered critically ill by the…

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