B-BIC: Translating Discoveries Into Products


A road map to commercialization


Grant funding up to $350,000 per project


Built with 16 institutions and the NIH


Boston Biomedical Innovation Center (B-BIC) is a life sciences accelerator funded by the National Institutes of Health and our member institutions to increase the return on investment in research. We speed the translation of research technologies into products for doctors and their patients, for the good of society.

Our members are a consortium of academic medical centers in Boston including Brigham and Women’s Hospital, Harvard Medical School, Massachusetts General Hospital, and the Massachusetts Institute of Technology.

Grant Funding

B-BIC provides funding for technology development and translational research, including regulatory, reimbursement, and business development aspects that are part of an overall commercialization strategy.

Project Management
Skills Development
External Partnerships

Clinical Domains


Technical Domains


Congratulations Dr. Sylvie Breton!

May 27, 2019

TITLE: Diagnostic for Acute Kidney Injury Associated with Cardiovascular Diseases TYPE OF AWARD: Drive TECHNOLOGY TYPE:  Diagnostic INSTITUTION: MGH   DESCRIPTION:  Acute kidney injury (AKI) is a frequent complication in hospitalized patients, including those undergoing cardiac surgery. However, two critical barriers to the clinical management of these critically ill patients remain the need for better methods…

Read More

New Award: Congratulations Dr. Robert Flaumenhaft!

May 27, 2019

TITLE: A Rapid, Inexpensive Platelet Function Test TYPE OF AWARD: Pilot CLINICAL AREA:  Blood INSTITUTION: BIDMC DESCRIPTION:  Antiplatelet agents such as clopidogrel and aspirin are used in the treatment of heart attacks and strokes and are among the most commonly used drugs in the U.S. Problems associated with these drugs include bleeding risk (which complicates invasive…

Read More

SPECIALIST SERIES: What Is An Investible Hypothesis?

May 26, 2019

By Jay Knowles Partner, Innovation Many venture capitalists look for opportunities to invest in a company or a project such that if it reaches a certain inflection point, that company will become significantly more valuable, and what it will cost to get it to that point. As an example, investors often like to see how…

Read More

Venture Adventure: Exploring the Role of the Inventor in Commercialization

February 21, 2019

Written by Carl Berke, PhD. Partner at the Partners Innovation Fund Thomas Edison famously remarked, “Invention is 1% inspiration and 99% perspiration”. The Wizard of Menlo Park was a prolific inventor who never left his lab, but his intellectual property was adopted by a plethora of companies who translated his technology into products that delighted…

Read More

Specialist Series: Understanding And Articulating Your Financials And Funding Requirements

January 7, 2019

By Lesley Watts When describing the financial support necessary to develop a technology, the first step is to be clear about the scope of the work you are addressing, as no single source of funding will be able to support all of the associated R&D costs.  Anyone who is assessing your project plan will want…

Read More


February 5, 2018

Q:  Do I need to have slides?  A:  Pitches only need to address the suggested elements.  Use of reference materials or other visual elements is welcome if they help convey the product concept and can be shared using your laptop screen.  AV equipment will not be available. Q:  How formal will the pitches be? A:…

Read More

FAST PITCH FOR FUNDING: Quick Tips for a successful pitch

August 14, 2018

Keep pitch short and focused on the technology and its commercial application. Limit the discussion of preliminary results, and focus on the most relevant results with conclusions – not data. Present the science within the context of the business strategy.   OUR NEXT FAST PITCH FOR FUNDING is Wednesday, January 30, 2019  from 10am – 12pm at NORTHEASTERN UNIVERSITY,…

Read More

Specialist Series: Building Your Project Plan

November 13, 2018

Co-authored by Erin McKenna, B-BIC Deputy Director & Ron Blackman, B-BIC Sr. Project Manager. When considering a development path needed to move technology to the clinic and beyond, it’s essential to address two questions:  Who will support the development of your technology, and what will they want to see to believe it can be commercialized? Who Will Support…

Read More

New Award: Congratulations Dr. Darren Roblyer

November 13, 2018

TITLE: CardioptOx: A new real-time quantitative cardio-pulmonary monitoring technique for improved patient care. TYPE OF AWARD: Pilot TECHNOLOGY TYPE: Diagnostic Device CLINICAL AREA:  Heart INSTITUTION: Boston University DESCRIPTION: Approximately 600,000 deaths per year are attributed to cardiopulmonary disease in the US. Many patients suffering from cardiopulmonary disease experience complications that require hospital and intensive care unit (ICU) stays.…

Read More

Specialist Series: Reimbursement Basics

October 19, 2018

Contributed by Ed Berger Principal Larchmont Strategic Advisors Reimbursement strategy counsel to companies across the life sciences spectrum   A basic understanding of the healthcare reimbursement system is an important success factor for any entrepreneur developing a new medical product. Reimbursement is critical to opportunity assessment, business plan development, investor due diligence, and commercial success.  The…

Read More

Specialist Series: A Brief Introduction to Intellectual Property

September 11, 2018

Contributed by Lesley Watts, Director of B-BIC Operations & Finance Intellectual property is the product of a person’s creativity and it can take several forms including patents, copyright, trademarks, and trade secrets.  Patents play a key role in innovation and economic development, particularly in the life sciences, because they allow the patent holder to capture the…

Read More

Success Stories: B-BIC’s Work With Platelet Biogenesis

September 11, 2018

WATCH:  B-BIC’s Work With Platelet Biogenesis One of B-BIC’s first grant recipients was Jonathan Thon, a researcher based at Brigham and Women’s Hospital. Jonathan and his team had been researching two technologies necessary for producing platelets outside of the body. They had achieved promising results that demonstrated a microfluidic platform could simulate bone marrow physiological…

Read More

Specialist Series: The Regulatory Path

April 17, 2018

Contributed by John Randle, Phd B-BIC COACH PRINCIPAL, RANDOM WALK VENTURES, LLC COO, KANTUM BIO   Most new technologies and products will require regulatory scrutiny and approval prior to marketing.  These requirements vary widely depending on the nature of the technology/product and their intended medical use, as well as the regulatory precedent set by existing…

Read More

New Awards: B-BIC selects three new technologies to award support for commercial development.

April 7, 2016

RECIPIENT:  Dr. Ehud Schmidt TITLE: An MRI-Compatible Voltage Device Tracking For Multimodality Electrophysiology TYPE OF AWARD:  PILOT INSTITUTION: Brigham and Women’s Hospital DESCRIPTION:  Ehud Schmidt, PhD, Director of Engineering Physics in the Department of Radiology, Brigham and Women’s Hospital, and Associate Professor at Harvard Medical School receives a Pilot award to develop MRI-compatible voltage device tracking for multimodality…

Read More

New Awards: B-BIC Supports New Technologies For Commercial Development

January 6, 2016

RECIPIENT: Dr. Warren Zapol TITLE: Portable and Affordable Lightweight NO Generator TYPE OF AWARD:  DRIVE INSTITUTION: MGH DESCRIPTION:  Warren Zapol, MD, Director of the MGH Anesthesia Center for Critical Care Research at Massachusetts General Hospital, receives a DRIVE award to develop electric nitric oxide generation for medical purposes.  Inhaled nitric oxide (NO) was approved by the FDA…

Read More